Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477094 | 0.93 | LTA4H (0.58) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8475899 | 0.89 | HRH3 (0.45) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8472006 | 0.88 | HTT (0.52) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8472630 | 0.87 | POLB (0.45) | KDM4EALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL8472363 | 0.86 | POLB (0.47) | KDM4EALDH1A1LMNAALOX15 | |
| SCHEMBL8901044 | 0.85 | NPY1R (0.41) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8473412 | 0.83 | LTA4H (0.51) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8474563 | 0.83 | LTA4H (0.50) | LTA4HSMN1; SMN2KDM4EALDH1A1HTT | |
| SCHEMBL8475107 | 0.82 | KDM4E (0.45) | SMN1; SMN2KDM4EALDH1A1HTTTP53 | |
| SCHEMBL8477333 | 0.82 | HTR7 (0.48) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |