SCHEMBL8475975

SCHEMBL8475975

COc1ccc(-c2nn(C)c(OC(F)F)c2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL3 Q96RI0 1/20 0.38
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
ATM Q13315 1/20 0.38
NPC1 O15118 2/20 0.37
RAB9A P51151 2/20 0.37
KDM4E B2RXH2 4/20 0.37
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.35
PTGS2 P35354 1/20 0.35
ALDH1A1 P00352 3/20 0.35
TP53 P04637 1/20 0.35
MAT2A P31153 1/20 0.35
MAPT P10636 2/20 0.35
NPSR1 Q6W5P4 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
TGFBR1 P36897 1/20 0.34
MAPK14 Q16539 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7707584 0.87 KDM4E (0.38) KDM4EPOLBALDH1A1TP53MAPT
SCHEMBL8888868 0.86 MAPT (0.36) KMT2ANPC1RAB9AKDM4ELMNA
SCHEMBL8471696 0.84 KEAP1 (0.35) KDM4EALDH1A1NPSR1SMN1; SMN2MAPK14
SCHEMBL8474436 0.84 SMN1; SMN2 (0.32) NPSR1SMN1; SMN2
SCHEMBL8471279 0.84 PDE4D (0.36) KDM4EALDH1A1NPSR1SMN1; SMN2KDM4C
SCHEMBL8478367 0.83 SRC (0.37) F2RL3MEN1KMT2ANPC1RAB9A
SCHEMBL6919426 0.82 SLC34A1 (0.41) KDM4EMAT2A
SCHEMBL8472612 0.81 TRPV4 (0.33) MEN1KMT2AKDM4EPOLBPTGS2
SCHEMBL8471677 0.81 AMY1A (0.38) KDM4ELMNAPOLBPTGS2ALDH1A1
SCHEMBL6674684 0.80 CHRNB2 (0.35) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5861359-A WHEAT, SOYBEANS, CORN; PRE- AND POSTEMERGENCE HERBICIDES FMC CORPORATION (US) 1999-01-19 US disclosed
WO-1997005115-A1 HERBICIDAL PHENYLMETHOXYPHENYL HETEROCYCLES FMC CORPORATION (US) 1997-02-13 WO disclosed