SCHEMBL847600

SCHEMBL847600

CC(C)(C)n1c(=O)ccc2ccccc21

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CA12 O43570 3/20 0.57
▸ CA9 Q16790 3/20 0.57
▸ BRD4 O60885 1/20 0.57
▸ BRPF1 P55201 1/20 0.57
▸ KAT2B Q92831 1/20 0.57
▸ BRD9 Q9H8M2 1/20 0.57
▸ ALDH1A1 P00352 5/20 0.38
▸ MAPT P10636 1/20 0.38
▸ KMT2A Q03164 2/20 0.38
▸ MAPK1 P28482 1/20 0.37
▸ CA1 P00915 1/20 0.36
▸ NOTUM Q6P988 1/20 0.36
▸ SMN1; SMN2 Q16637 4/20 0.34
▸ PRKD3 O94806 1/20 0.34
▸ PRKCG P05129 1/20 0.34
▸ PRKCB P05771 1/20 0.34
▸ PRKCA P17252 1/20 0.34
▸ PRKACA P17612 1/20 0.34
▸ PRKACG P22612 1/20 0.34
▸ PRKACB P22694 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29941678 0.82 CA12 (0.53) CA12CA9BRD4BRPF1KAT2B
SCHEMBL1052785 0.82 CA12 (0.53) CA12CA9BRD4BRPF1KAT2B
SCHEMBL9096468 0.78 CA12 (0.46) CA12CA9BRD4BRPF1KAT2B
SCHEMBL17637285 0.76 HTR2C (0.37) CA12CA9BRD4BRPF1KAT2B
SCHEMBL12604116 0.74 PDE3B (0.36) CA12CA9BRD4BRPF1KAT2B
SCHEMBL29967380 0.72 BRPF1 (1.00) CA12CA9BRD4BRPF1KAT2B
SCHEMBL248619 0.72 BRPF1 (1.00) CA12CA9BRD4BRPF1KAT2B
SCHEMBL14584044 0.72 SLC6A2 (0.45) CA12CA9BRD4BRPF1KAT2B
Hydrochloric Acid SCHEMBL30419636 0.71 BRPF1 (0.96) CA12CA9BRD4BRPF1KAT2B
Hydrochloric Acid SCHEMBL1236989 0.71 BRPF1 (0.96) CA12CA9BRD4BRPF1KAT2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12252473-B2 Preparation methods of quinolone compounds and intermediates thereof Chongqing University of Arts and Sciences (CN) 2025-03-18 — — US disclosed
US-20240400522-A1 PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF Chongqing University of Arts and Sciences (CN) 2024-12-05 — — US disclosed
US-12029683-B2 Ocular implant and delivery system ALCON INC. (CH) 2024-07-09 — — US disclosed
US-20240207091-A1 DRUG DELIVERY IMPLANTS WITH BI-DIRECTIONAL DELIVERY CAPACITY AND METHODS OF USING SAME GLAUKOS CORP (US) 2024-06-27 — — US disclosed
US-11992551-B2 Implants with controlled drug delivery features and methods of using same GLAUKOS CORPORATION (US) 2024-05-28 — — US disclosed
EP-4371535-A2 OCULAR IMPLANT Alcon Inc. (CH) 2024-05-22 — — EP disclosed
US-20240108219-A1 INTRAOCULAR PHYSIOLOGICAL SENSOR GLAUKOS CORPORATION 2024-04-04 — — US disclosed
EP-3755287-B1 OCULAR IMPLANT ALCON INC (CH) 2024-04-03 — — EP disclosed
US-11944573-B2 System and method for delivering multiple ocular implants GLAUKOS CORPORATION (US) 2024-04-02 — — US disclosed
US-11938058-B2 Ocular implant and delivery system ALCON INC. (CH) 2024-03-26 — — US disclosed
US-20130253528-A1 SYSTEM AND METHOD FOR DELIVERING MULTIPLE OCULAR IMPLANTS GLAUKOS CORPORATION (US) 2013-09-26 — — US disclosed
US-20130090534-A1 INTRAOCULAR PHYSIOLOGICAL SENSOR GLAUKOS CORPORATION 2013-04-11 — — US disclosed
WO-2013040079-A1 INTRAOCULAR PHYSIOLOGICAL SENSOR DOSE MEDICAL CORPORATION (US) 2013-03-21 — — WO disclosed
WO-2012158910-A2 COMPOSITIONS AND METHODS FOR TREATING RETINAL DISEASES THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2012-11-22 — — WO disclosed
US-20120165933-A1 UVEOSCLERAL DRUG DELIVERY IMPLANT AND METHODS FOR IMPLANTING THE SAME DOSE MEDICAL CORPORATION (US) 2012-06-28 — — US disclosed
WO-2012071476-A2 DRUG ELUTING OCULAR IMPLANT HAFFNER DAVID (US) 2012-05-31 — — WO disclosed
US-20120078362-A1 DRUG ELUTING OCULAR IMPLANT DOSE MEDICAL CORPORATION (US) 2012-03-29 — — US disclosed
EP-2432420-A1 DRUG ELUTING OCULAR IMPLANT Dose Medical Corporation (US) 2012-03-28 — — EP disclosed
WO-2010135369-A1 DRUG ELUTING OCULAR IMPLANT DOSE MEDICAL CORPORATION (US) 2010-11-25 — — WO disclosed
WO-2010093945-A2 UVEOSCLERAL DRUG DELIVERY IMPLANT AND METHODS FOR IMPLANTING THE SAME GLAUKOS CORPORATION (US) 2010-08-19 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240400522-A1 PREPARATION METHODS OF QUINOLONE COMPOUNDS AND INTERMEDIATES THEREOF NQO2, MRPL21, RECQL CA12 3613/4885CA9 3870/4885BRD4 2009/4885
US-12252473-B2 Preparation methods of quinolone compounds and intermediates thereof NQO2, MRPL21, RECQL CA12 3613/4885CA9 3870/4885BRD4 2009/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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