Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | BRD4 | O60885 | 1/20 | 0.53 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.53 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.53 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 4/20 | 0.38 |
| ▸ | CCND1 | P24385 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKCG | P05129 | 1/20 | 0.35 |
| ▸ | PRKCB | P05771 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | PRKACG | P22612 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1052785 | 1.00 | CA12 (0.53) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL847600 | 0.82 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL1054493 | 0.74 | CA12 (0.57) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL9372428 | 0.73 | CA12 (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL16896766 | 0.73 | CA12 (0.47) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL9096468 | 0.72 | CA12 (0.46) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL7209185 | 0.71 | NR3C1 (0.44) | CA12CA9 | |
| SCHEMBL1052080 | 0.71 | CA12 (0.59) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL23272041 | 0.71 | HSD17B10 (0.33) | CA12CA9BRD4BRPF1KAT2B | |
| SCHEMBL29947955 | 0.71 | HSD17B10 (0.33) | CA12CA9BRD4BRPF1KAT2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4093735-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | Syngenta Crop Protection AG (CH) | 2022-11-30 | — | — | EP | disclosed |
| US-11446398-B2 | Regulated biocircuit systems | OBSIDIAN THERAPEUTICS, INC. (US) | 2022-09-20 | — | — | US | disclosed |