Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL847600 | 0.78 | CA12 (0.57) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL1052785 | 0.72 | CA12 (0.53) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL29941678 | 0.72 | CA12 (0.53) | CA12BRD4BRPF1CA9KAT2B | |
| Bicarbonate SCHEMBL10970799 | 0.69 | BRPF1 (0.85) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL30887024 | 0.69 | PPARG (0.37) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL30887023 | 0.69 | PPARG (0.37) | KMT2AMAPTCYP2C19HIF1ACYP1A2 | |
| SCHEMBL7592805 | 0.68 | CHRM3 (0.57) | CHRM3 | |
| SCHEMBL27888039 | 0.67 | MAPT (0.64) | KMT2AMAPTCYP2C19HIF1ATSHR | |
| SCHEMBL6581393 | 0.67 | CA12 (0.52) | CA12BRD4BRPF1CA9KAT2B | |
| SCHEMBL2127676 | 0.67 | CYP2B6 (0.59) | CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-8003139-A | — | — | None | — | — | JP | disclosed |
| JP-H083139-A | 2-OXO-1-QUINOLINYLMETHYLPHENYLACETIC ACID DERIVATIVE | BAYER AG | 1996-01-09 | — | — | JP | disclosed |
| EP-0608709-A1 | 2-Oxo-quinolin-1-yl-methyl-phenylacetic acid derivatives as angiotensin II Antagonists | BAYER AG (DE) | 1994-08-03 | — | — | EP | disclosed |