SCHEMBL8476285

SCHEMBL8476285

C=CC(=O)NCc1ccc(OCC)cc1

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.60
KMT2A Q03164 3/20 0.60
TGM2 P21980 1/20 0.59
ACACB O00763 2/20 0.59
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
EPHX2 P34913 1/20 0.55
NR1H4 Q96RI1 1/20 0.55
LMNA P02545 3/20 0.52
SMN1; SMN2 Q16637 1/20 0.49
CYP3A4 P08684 1/20 0.47
MAPK1 P28482 1/20 0.47
ALDH1A1 P00352 1/20 0.47
MAPT P10636 1/20 0.47
POLB P06746 1/20 0.46
XDH P47989 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8995961 0.93 MEN1 (0.60) MEN1KMT2ATGM2ACACBNPC1
SCHEMBL11927835 0.87 TGM2 (0.63) MEN1KMT2ATGM2ACACBNPC1
SCHEMBL4743993 0.84 TGM2 (0.63) MEN1KMT2ATGM2NPC1RAB9A
SCHEMBL732934 0.83 TGM2 (0.81) MEN1KMT2ATGM2LMNAMAPK1
SCHEMBL8476754 0.82 ROCK2 (0.55) KMT2ATGM2ACACBEPHX2SMN1; SMN2
SCHEMBL8584863 0.80 TGM2 (0.51) MEN1KMT2ATGM2ACACBNPC1
SCHEMBL5241790 0.80 NPC1 (0.61) MEN1KMT2ANPC1RAB9AEPHX2
SCHEMBL15514715 0.80 NPC1 (0.66) MEN1KMT2ANPC1RAB9AEPHX2
SCHEMBL21392882 0.80 RAB9A (0.55) MEN1KMT2ANPC1RAB9AEPHX2
SCHEMBL30553603 0.80 NR4A2 (0.55) TGM2NPC1RAB9AEPHX2LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5998091-A COPOLYMER OF A MONOFUNCTIONAL MACROMONOMER HAVING A PARTICULAR POLYMERIZABLE DOUBLE BOND-CONTAINING GROUP SITUATED AT ONLY ONE END OF THE MAIN CHAIN, A QUATERNARY AMMONIUM SALT AND AN AMIDE FUJI PHOTO FILM CO., LTD. (JP) 1999-12-07 US disclosed
EP-0505972-B1 Process for producing styrenic copolymer IDEMITSU KOSAN CO (JP) 1997-06-11 EP disclosed
EP-0490269-B1 Graft copolymer and process for producing the same IDEMITSU KOSAN CO (JP) 1996-02-28 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0505972-A2 Process for producing styrenic copolymer IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-09-30 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed