Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 6/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.54 |
| ▸ | CNR1 | P21554 | 4/20 | 0.53 |
| ▸ | CNR2 | P34972 | 3/20 | 0.53 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17774887 | 0.77 | NSD2 (0.58) | KMT2AHPGDCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL4639773 | 0.77 | EPHX2 (0.66) | EPHX2NPSR1CNR1CNR2MTNR1A | |
| SCHEMBL5947652 | 0.77 | EPHX2 (0.81) | EPHX2NPSR1CNR1CNR2MTNR1A | |
| SCHEMBL8473138 | 0.74 | NAAA (0.56) | EPHX2NPSR1CNR1CNR2ALDH1A1 | |
| SCHEMBL6887760 | 0.73 | NAAA (0.48) | HPGDALDH1A1LMNA | |
| SCHEMBL3138003 | 0.73 | MEN1 (0.48) | MEN1KMT2ALMNA | |
| SCHEMBL5947857 | 0.73 | EPHX2 (0.63) | EPHX2NPSR1CNR1CNR2MTNR1A | |
| SCHEMBL5948102 | 0.73 | EPHX2 (1.00) | EPHX2NPSR1CNR1CNR2MTNR1A | |
| SCHEMBL3132663 | 0.72 | NSD2 (0.49) | MEN1KMT2AHPGDALDH1A1LMNA | |
| SCHEMBL8477486 | 0.72 | HTR4 (0.43) | CNR1MEN1KMT2AALDH1A1TPSAB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5872115-A | COMPOUNDS FOR TREATMENT OF HYPERCHOLESTEROLEMIA, ISCHEMIC HEART DISEASE, CEREBROVASCULAR DISEASE OR ATHEROSCLEROSIS | GRELAN PHARMACEUTICAL CO. LTD. (JP) | 1999-02-16 | — | — | US | disclosed |
| EP-0742208-A1 | 2-Ureido-benzamide derivatives | GRELAN PHARMACEUTICAL CO., LTD. (JP) | 1996-11-13 | — | — | EP | disclosed |