Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | EDNRB | P24530 | 5/20 | 0.43 |
| ▸ | EDNRA | P25101 | 5/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8475895 | 0.85 | PTGS2 (0.54) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8473431 | 0.84 | ALDH1A1 (0.51) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8348668 | 0.84 | PTGS2 (0.53) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8474218 | 0.83 | ALDH1A1 (0.50) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8479939 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8476337 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8478927 | 0.82 | ALDH1A1 (0.49) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8476782 | 0.81 | ALDH1A1 (0.46) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8473498 | 0.81 | ALDH1A1 (0.48) | ALDH1A1NPSR1PKMPTGS2MT-CO2 | |
| SCHEMBL8474054 | 0.80 | ALDH1A1 (0.43) | ALDH1A1NPSR1PKMPTGS2MT-CO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5859257-A | ANTIINFLAMMATORY, ANTIARTHRITIC AGENTS | G. D. SEARLE & CO. (US) | 1999-01-12 | — | — | US | disclosed |