Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALB | P02768 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476369 | 1.00 | LMNA (0.38) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2284109 | 0.91 | LMNA (0.37) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9368222 | 0.89 | LMNA (0.36) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9368232 | 0.89 | LMNA (0.36) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9372470 | 0.88 | LMNA (0.35) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9372482 | 0.88 | LMNA (0.35) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24922883 | 0.87 | LMNA (0.34) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL12373120 | 0.87 | TK1 (0.39) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL2284113 | 0.87 | TK1 (0.39) | LMNAALOX12ADRA1ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6819502 | 0.83 | LMNA (0.39) | LMNAALOX12ADRA1ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6002003-A | Cyanine dye activating group with improved coupling selectivity | BECKMAN INSTRUMENTS, INC. (US) | 1999-12-14 | — | — | US | disclosed |
| US-5625081-A | XANTHENE DYE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-04-29 | — | — | US | disclosed |
| US-5608063-A | Method, system and reagents for DNA sequencing | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-03-04 | — | — | US | disclosed |
| US-5558991-A | DNA sequencing method using acyclonucleoside triphosphates | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-09-24 | — | — | US | disclosed |
| EP-0309969-B1 | Method of gene mapping | DU PONT (US) | 1995-07-19 | — | — | EP | disclosed |
| EP-0252683-B1 | Process and reagents for DNA sequence analysis | DU PONT (US) | 1995-01-18 | — | — | EP | disclosed |
| EP-0251786-B1 | Alkynylamino-nucleotides | DU PONT (US) | 1994-11-30 | — | — | EP | disclosed |
| US-5332666-A | Reporter-labeled chain terminator reacted with DNA nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-07-26 | — | — | US | disclosed |
| US-5306618-A | Using xanthene dye reporter labeled DNA fragments | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-04-26 | — | — | US | disclosed |
| US-5242796-A | Fluorescent xanthene dye | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-09-07 | — | — | US | disclosed |
| US-5151507-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-09-29 | — | — | US | disclosed |
| US-5102785-A | Cleaving to produce DNA fragment which are then end labeled with reporter, again cleaved to produce short fragment, separatiion; analysis | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-04-07 | — | — | US | disclosed |
| US-5047519-A | Alkynylamino-nucleotides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-09-10 | — | — | US | disclosed |