Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | BCL9 | O00512 | 1/20 | 0.32 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PDE4A | P27815 | 2/20 | 0.32 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8474699 | 0.91 | MAPT (0.37) | HPGDMAPTKDM4EGAASLC10A2 | |
| SCHEMBL8581223 | 0.84 | MAPK1 (0.36) | MAPTKDM4EGAASLC10A2MGAM | |
| SCHEMBL8482345 | 0.83 | SLC10A2 (0.38) | HPGDMAPTKDM4EGAASLC10A2 | |
| SCHEMBL8479043 | 0.81 | MAPK1 (0.37) | HPGDMAPTKDM4ESLC10A2KMT2A | |
| SCHEMBL8478228 | 0.80 | MAPK1 (0.35) | HPGDMAPTKDM4EFAAHKMT2A | |
| SCHEMBL8581095 | 0.80 | MAPK1 (0.36) | MAPTKDM4EGAASLC10A2MGAM | |
| SCHEMBL8475146 | 0.78 | MGAM (0.42) | HPGDMAPTKDM4EGAAMGAM | |
| SCHEMBL8477805 | 0.76 | PDE4B (0.40) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL8475245 | 0.75 | MAPT (0.38) | HPGDMAPTGAAMGAMSI | |
| SCHEMBL8475018 | 0.74 | PDE4B (0.38) | ALDH1A1CYP3A4PDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6004988-A | Carboxylic acid derivatives, their preparation and their use | BASF AKTIENGESELLSCHAFT (DE) | 1999-12-21 | — | — | US | disclosed |