Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.42 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.42 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8472787 | 0.88 | DRD2 (0.40) | CACNA2D1CACNA1BCACNB1HTTALDH1A1 | |
| SCHEMBL8477103 | 0.85 | ALDH1A1 (0.45) | HTTMAPK14ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8472629 | 0.85 | CACNA2D1 (0.40) | CACNA2D1CACNA1BCACNB1ALDH1A1KDM4E | |
| SCHEMBL8473313 | 0.84 | ALDH1A1 (0.44) | HTTMAPK14ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8475503 | 0.81 | CYP1A2 (0.44) | HTTMAPK14ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8477098 | 0.81 | MEN1 (0.41) | HTTMAPK14ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8472353 | 0.81 | ALDH1A1 (0.45) | HTTMAPK14ALDH1A1KDM4EMAPK1 | |
| SCHEMBL8473693 | 0.80 | MAPK1 (0.41) | CACNA2D1CACNA1BCACNB1HTTALDH1A1 | |
| SCHEMBL8473768 | 0.79 | SLC6A2 (0.41) | CACNA2D1CACNA1BCACNB1ALDH1A1KDM4E | |
| SCHEMBL8472003 | 0.79 | HTR2C (0.43) | HTTALDH1A1KDM4ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |