Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8473313 | 0.99 | ALDH1A1 (0.44) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8475503 | 0.92 | CYP1A2 (0.44) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472353 | 0.87 | ALDH1A1 (0.45) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8900037 | 0.85 | DRD2 (0.47) | MAPK1LMNATSHRHTR7HTT | |
| SCHEMBL8477100 | 0.85 | CACNA2D1 (0.42) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472630 | 0.83 | POLB (0.45) | ALDH1A1KDM4EMEN1KMT2AHTR7 | |
| SCHEMBL7609464 | 0.82 | ALDH1A1 (0.42) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472363 | 0.82 | POLB (0.47) | ALDH1A1KDM4EALOX15HSD17B10LMNA | |
| SCHEMBL8476087 | 0.82 | POLB (0.42) | ALDH1A1KDM4EMAPK1HPGDALOX15 | |
| SCHEMBL8472878 | 0.78 | AKR1C3 (0.47) | TSHRHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |