Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 4/20 | 0.35 |
| ▸ | GSK3B | P49841 | 3/20 | 0.34 |
| ▸ | PRKCA | P17252 | 2/20 | 0.34 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8466339 | 0.86 | CCNT1 (0.44) | MYLKGSK3BPRKCACCNT1CDK9 | |
| SCHEMBL8477176 | 0.79 | MYLK (0.35) | MYLKGSK3BPRKCACDK9ADRB2 | |
| SCHEMBL8113582 | 0.79 | GSK3B (0.55) | MYLKGSK3BPRKCA | |
| SCHEMBL8477960 | 0.78 | CCNT1 (0.42) | GSK3BPRKCACCNT1CDK9MEN1 | |
| SCHEMBL8467099 | 0.73 | HTR2C (0.38) | MYLKGSK3BPRKCAMEN1USP2 | |
| SCHEMBL8477363 | 0.72 | MYLK (0.38) | MYLKGSK3BPRKCACCNT1CDK9 | |
| SCHEMBL8122760 | 0.71 | GSK3B (0.54) | MYLKGSK3BPRKCACCNT1CDK9 | |
| SCHEMBL8124325 | 0.69 | GSK3B (0.61) | GSK3BPRKCACCNT1CDK9 | |
| SCHEMBL8122774 | 0.68 | PRKCA (0.63) | GSK3BPRKCACCNT1CDK9 | |
| SCHEMBL8113347 | 0.68 | PRKCA (0.63) | GSK3BPRKCACCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |