Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYLK | Q15746 | 5/20 | 0.35 |
| ▸ | GSK3B | P49841 | 6/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | PRKCA | P17252 | 3/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | PAK4 | O96013 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467099 | 0.90 | HTR2C (0.38) | MYLKGSK3BLCKIGF1RGSK3A | |
| SCHEMBL8477363 | 0.85 | MYLK (0.38) | MYLKGSK3BLCKIGF1RGSK3A | |
| SCHEMBL8477172 | 0.79 | MYLK (0.35) | MYLKGSK3BLCKIGF1RGSK3A | |
| SCHEMBL8482795 | 0.73 | CCNT1 (0.44) | GSK3BPRKCAPIM1PRKACACDK9 | |
| SCHEMBL8477329 | 0.73 | HTR2C (0.38) | GSK3BLCKIGF1RGSK3ACDK7 | |
| SCHEMBL8466339 | 0.68 | CCNT1 (0.44) | MYLKGSK3BPRKCAFLT3CDK9 | |
| SCHEMBL8113582 | 0.68 | GSK3B (0.55) | MYLKGSK3BPRKCA | |
| SCHEMBL8619768 | 0.65 | PIM1 (0.43) | GSK3BPRKCAPIM1PRKACACDK9 | |
| SCHEMBL8467187 | 0.64 | MEN1 (0.45) | MYLKGSK3BPRKCAPIM1PRKACA | |
| SCHEMBL8122760 | 0.64 | GSK3B (0.54) | MYLKGSK3BPRKCACDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |