Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 2/20 | 0.44 |
| ▸ | CDK9 | P50750 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | USP2 | O75604 | 5/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | CASP1 | P29466 | 3/20 | 0.42 |
| ▸ | CASP7 | P55210 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HBB | P68871 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | PRKCA | P17252 | 3/20 | 0.41 |
| ▸ | GSK3B | P49841 | 3/20 | 0.41 |
| ▸ | MYLK | Q15746 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477172 | 0.86 | MYLK (0.35) | CCNT1CDK9MEN1USP2CYP1A2 | |
| SCHEMBL8477960 | 0.84 | CCNT1 (0.42) | CCNT1CDK9MEN1USP2CYP1A2 | |
| SCHEMBL8126914 | 0.79 | PRKCA (0.64) | CCNT1CDK9PRKCAGSK3BKDR | |
| SCHEMBL8619764 | 0.75 | CAMK2D (0.57) | CCNT1CDK9PRKCAPTPRCCCNA2 | |
| SCHEMBL8467099 | 0.74 | HTR2C (0.38) | MEN1USP2CYP1A2CYP3A4KMT2A | |
| SCHEMBL8477363 | 0.73 | MYLK (0.38) | CCNT1CDK9MEN1USP2CYP1A2 | |
| SCHEMBL8113347 | 0.73 | PRKCA (0.63) | CCNT1CDK9PRKCAGSK3BCCNA2 | |
| SCHEMBL8122774 | 0.73 | PRKCA (0.63) | CCNT1CDK9PRKCAGSK3BCCNA2 | |
| SCHEMBL25282614 | 0.71 | CAMK2D (0.57) | CCNT1CDK9CCNA2CDK2 | |
| SCHEMBL8923158 | 0.71 | GSK3B (0.47) | CCNT1CDK9PRKCAGSK3BKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |
| US-5883114-A | TREATING CANCEROUS TUMORS, INFLAMMATORY DISEASES, AND ALLERGIES | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-03-16 | — | — | US | disclosed |