Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HTR2B | P41595 | 1/20 | 0.38 |
| ▸ | HTR5A | P47898 | 1/20 | 0.38 |
| ▸ | PRKD1 | Q15139 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 7/20 | 0.36 |
| ▸ | PRKCA | P17252 | 4/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 2/20 | 0.35 |
| ▸ | IGF1R | P08069 | 2/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | CDK7 | P50613 | 2/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | AURKA | O14965 | 1/20 | 0.34 |
| ▸ | PAK4 | O96013 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477363 | 0.83 | MYLK (0.38) | HTR2CHTR2BHTR5APRKD1TDP1 | |
| SCHEMBL8467099 | 0.83 | HTR2C (0.38) | HTR2CHTR2BHTR5AGSK3BPRKCA | |
| SCHEMBL8482610 | 0.74 | PRKACA (0.47) | PRKD1TDP1GSK3BPRKCAPIM1 | |
| SCHEMBL8477176 | 0.73 | MYLK (0.35) | GSK3BPRKCALCKIGF1RGSK3A | |
| SCHEMBL8619768 | 0.72 | PIM1 (0.43) | GSK3BPRKCAPIM1PRKACACDK9 | |
| SCHEMBL8482795 | 0.71 | CCNT1 (0.44) | GSK3BPRKCAPIM1PRKACACDK9 | |
| SCHEMBL8477332 | 0.69 | PRKD1 (0.55) | PRKD1TDP1GSK3BPRKCAPIM1 | |
| SCHEMBL8477326 | 0.68 | GSK3B (0.40) | HTR2CHTR2BHTR5APRKD1TDP1 | |
| SCHEMBL8523454 | 0.67 | PTPRC (0.40) | GSK3BPRKCAPIM1PRKACACDK9 | |
| Hydrochloric Acid SCHEMBL8655886 | 0.67 | PRKCE (0.49) | PRKD1GSK3BPRKCAPIM1PRKACA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5945440-A | Indolocarbazole imides and the use thereof | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1999-08-31 | — | — | US | disclosed |