Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 3/20 | 0.43 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | AHR | P35869 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.37 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.37 |
| ▸ | CDK2 | P24941 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8482610 | 0.89 | PRKACA (0.47) | PIM1AHRPTPRCCCNT1CDK9 | |
| SCHEMBL8482795 | 0.88 | CCNT1 (0.44) | PIM1CAMK2DAHRPTPRCCCNT1 | |
| SCHEMBL8477363 | 0.78 | MYLK (0.38) | CCNT1CDK9GSK3BPRKCA | |
| SCHEMBL8523454 | 0.76 | PTPRC (0.40) | PIM1CAMK2DAHRPTPRCCCNT1 | |
| SCHEMBL8467099 | 0.76 | HTR2C (0.38) | GSK3BALDH1A1LMNAPRKCA | |
| SCHEMBL8619764 | 0.75 | CAMK2D (0.57) | PIM1CAMK2DPTPRCRPS6KB1CCNT1 | |
| SCHEMBL8920200 | 0.74 | PRKCG (0.43) | PIM1CAMK2DPTPRCCCNT1CDK9 | |
| Hydrochloric Acid SCHEMBL8919122 | 0.74 | PRKCB (0.43) | PIM1CAMK2DPTPRCCCNT1CDK9 | |
| SCHEMBL25282614 | 0.73 | CAMK2D (0.57) | PIM1CAMK2DRPS6KB1CCNT1CDK9 | |
| SCHEMBL22534426 | 0.72 | GSK3B (0.49) | PTPRCCCNT1CDK9CCNE2CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5750555-A | NERVOUS SYSTEM DISORDERS; SKIN DISORDERS; IMMUNOLOGY | GOEDECKE AKTIENGESELLSCHAFT (DE) | 1998-05-12 | — | — | US | disclosed |