Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | NPY1R | P25929 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477351 | 0.92 | HRH3 (0.48) | HTTKDM4ERAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8477079 | 0.90 | HTT (0.48) | HTTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8474454 | 0.89 | LMNA (0.53) | HTTKDM4ENPC1RAB9ASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8474181 | 0.89 | KDM4E (0.52) | KDM4ERAB9ASMN1; SMN2ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL8476318 | 0.88 | KDM4E (0.50) | KDM4ERAB9ASMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL8472561 | 0.88 | HDAC3 (0.41) | EGFRLTA4HCHRM4HDAC3HDAC1 | |
| SCHEMBL8472006 | 0.87 | HTT (0.52) | HTTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8479145 | 0.87 | HTR2C (0.42) | NPC1RAB9ASMN1; SMN2L3MBTL1NPY1R | |
| SCHEMBL8472345 | 0.86 | SMN1; SMN2 (0.45) | HTTKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8474896 | 0.86 | EGFR (0.47) | HTTKDM4ENPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |