Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505777 | 0.85 | CA1 (0.50) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL16960994 | 0.82 | CA1 (0.42) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL696242 | 0.78 | TP53 (0.43) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1374548 | 0.78 | ALDH1A1 (0.56) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL1029593 | 0.78 | PDE4A (0.45) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL30873744 | 0.78 | ALDH1A1 (0.56) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL11358137 | 0.78 | TP53 (0.59) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL28338628 | 0.77 | ALDH1A1 (0.48) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL178447 | 0.76 | L3MBTL1 (0.46) | LMNATP53KDM4EALDH1A1CYP3A4 | |
| SCHEMBL14879898 | 0.76 | MAPT (0.42) | LMNATP53KDM4EALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5856334-A | ANTAGONIST FOR EOSINOPHILS | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-05 | — | — | US | disclosed |
| EP-0773219-A1 | IMIDAZOQUINOLINE DERIVATIVE | MOCHIDA PHARMACEUTICAL CO., LTD. (JP) | 1997-05-14 | — | — | EP | disclosed |