SCHEMBL8477754

SCHEMBL8477754

CC(=O)N1CCC(C(=O)O)CC1(C)NC(=O)Cc1ccc(C)cc1C

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
P2RX7 Q99572 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
RAB9A P51151 2/20 0.36
NPC1 O15118 1/20 0.36
POLB P06746 2/20 0.36
TSHR P16473 1/20 0.36
EPHX2 P34913 6/20 0.35
NOTUM Q6P988 1/20 0.34
CCR2 P41597 1/20 0.33
GAA P10253 1/20 0.32
HTT P42858 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8481630 0.86 EPHX2 (0.39) P2RX7MEN1KMT2AEPHX2NOTUM
SCHEMBL6767292 0.70 MEN1 (0.44) P2RX7MEN1KMT2ARAB9ANPC1
SCHEMBL8477759 0.69 NOTUM (0.36) MEN1KMT2ATSHREPHX2NOTUM
SCHEMBL8481382 0.69 EPHX2 (0.35) P2RX7MEN1KMT2AEPHX2
SCHEMBL6764668 0.68 ALDH1A1 (0.45) P2RX7MEN1KMT2ARAB9ANPC1
SCHEMBL8906307 0.68 LPAR1 (0.39) P2RX7RAB9ANPC1POLBL3MBTL1
SCHEMBL9045945 0.67 MEN1 (0.42) P2RX7MEN1KMT2ARAB9ANPC1
SCHEMBL8906980 0.67 NPC1 (0.41) P2RX7MEN1KMT2ARAB9ANPC1
SCHEMBL6767273 0.67 NPC1 (0.41) P2RX7MEN1KMT2ARAB9ANPC1
SCHEMBL8907075 0.67 NPC1 (0.39) P2RX7MEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5981567-A ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION BAYER AKTIENGESELLSCHAFT (DE) 1999-11-09 US disclosed