Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CASP1 | P29466 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9045439 | 0.89 | NPC1 (0.39) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9044569 | 0.85 | PYGL (0.35) | MEN1KMT2APOLBKDM4EALDH1A1 | |
| SCHEMBL9044691 | 0.84 | POLB (0.38) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL6767292 | 0.83 | MEN1 (0.44) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9045472 | 0.82 | EPHX2 (0.44) | KMT2AALDH1A1HPGDP2RX7CYP2D6 | |
| SCHEMBL9045049 | 0.79 | CYP3A4 (0.37) | MEN1KMT2ANPC1RAB9AKDM4E | |
| SCHEMBL6767098 | 0.79 | MEN1 (0.49) | MEN1KMT2ANPC1RAB9APOLB | |
| SCHEMBL9045730 | 0.76 | ALDH1A1 (0.46) | MEN1KMT2AKDM4EALDH1A1CYP2D6 | |
| SCHEMBL9046306 | 0.74 | ALOX15 (0.42) | MEN1KMT2APOLBP2RX7LMNA | |
| SCHEMBL9046338 | 0.72 | KMT2A (0.43) | MEN1KMT2AALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0706527-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AG (DE) | 1996-04-17 | — | — | EP | disclosed |
| WO-1995001358-A1 | SUBSTITUTED SPIROHETEROCYCLIC 1H-3-ARYLPYRROLIDINE-2,4-DIONE DERIVATIVES, METHODS OF PREPARING THEM AND THEIR USE AS PEST-CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 1995-01-12 | — | — | WO | disclosed |