Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850153 | 0.85 | ALDH1A1 (0.42) | ALDH1A1MDM2KMT2AMEN1HTT | |
| SCHEMBL7650191 | 0.82 | P2RX7 (0.38) | ALDH1A1MDM2KMT2AMEN1RAB9A | |
| SCHEMBL6767292 | 0.70 | MEN1 (0.44) | ALDH1A1KMT2AMEN1RAB9AP2RX7 | |
| SCHEMBL9045945 | 0.70 | MEN1 (0.42) | ALDH1A1KMT2AMEN1RAB9AP2RX7 | |
| SCHEMBL6767098 | 0.69 | MEN1 (0.49) | ALDH1A1KMT2AMEN1RAB9AP2RX7 | |
| SCHEMBL2586245 | 0.68 | ALDH1A1 (0.69) | ALDH1A1MDM2KMT2AMEN1RAB9A | |
| SCHEMBL8477754 | 0.68 | P2RX7 (0.37) | KMT2AMEN1RAB9AP2RX7HTT | |
| SCHEMBL5537920 | 0.68 | GRIN2B (0.63) | ALDH1A1KMT2AMEN1 | |
| SCHEMBL14865223 | 0.66 | P2RX7 (0.49) | ALDH1A1KMT2AMEN1RAB9AP2RX7 | |
| SCHEMBL27416738 | 0.66 | SMN1; SMN2 (0.45) | ALDH1A1SMN1; SMN2POLBEPHX2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6774133-B2 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 2004-08-10 | — | — | US | disclosed |
| US-20040009999-A1 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | FISCHER REINER (DE) | 2004-01-15 | — | — | US | disclosed |
| US-6555567-B1 | 2-oxo-3-aryl-4-hydroxy-1-aza-8-thiaspiro(4.5)decane derivatives of given formula; use as arthropodicide or nematicide | BAYER AKTIENGESELLSCHAFT (DE) | 2003-04-29 | — | — | US | disclosed |
| US-6479489-B1 | AN ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 2002-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040009999-A1 | Substituted spiroheterocyclic 1H-3-aryl-pyrrolidine-2,4-dione derivatives, processes for their preparation, and their use as pesticides | DDT, HPD, CAT | ALDH1A1 382/4885MDM2 2741/4885KMT2A 1459/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.