Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 8/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.33 |
| ▸ | CASP7 | P55210 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8481634 | 0.86 | KDM4E (0.36) | NOTUMEPHX2KDM4EGAATSHR | |
| SCHEMBL6764669 | 0.70 | NOTUM (0.38) | NOTUMEPHX2PDK2KDM4EGAA | |
| SCHEMBL8477754 | 0.69 | P2RX7 (0.37) | NOTUMEPHX2GAATSHRMEN1 | |
| SCHEMBL8481385 | 0.69 | NOTUM (0.33) | NOTUMKDM4EHSD17B10USP2HPGD | |
| SCHEMBL6767298 | 0.68 | POLB (0.38) | NOTUMKDM4EGAATSHRHSD17B10 | |
| SCHEMBL6767279 | 0.66 | ALDH1A1 (0.37) | NOTUMKDM4ETSHRMEN1KMT2A | |
| SCHEMBL8481630 | 0.65 | EPHX2 (0.39) | NOTUMEPHX2KDM4EGAAHSD17B10 | |
| SCHEMBL6767104 | 0.64 | HIF1A (0.38) | NOTUMTSHRMEN1KMT2AUSP2 | |
| SCHEMBL6764661 | 0.62 | OPRM1 (0.40) | NOTUMKDM4ETSHRMEN1KMT2A | |
| SCHEMBL6764663 | 0.61 | DRD2 (0.38) | KDM4ETSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5981567-A | ARTHROPODICIDAL OR NEMATICIDAL COMPOSITION | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-09 | — | — | US | disclosed |