Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.57 |
| ▸ | EBP | Q15125 | 3/20 | 0.52 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.52 |
| ▸ | BCHE | P06276 | 3/20 | 0.52 |
| ▸ | ACHE | P22303 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 3/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221522 | 0.84 | TSHR (0.55) | — | |
| SCHEMBL1984870 | 0.83 | DRD2 (0.56) | EBPSIGMAR1BCHEACHEDRD2 | |
| SCHEMBL15537810 | 0.83 | THRA (0.59) | BCHEACHELMNASCN1ASCN2A | |
| SCHEMBL6539277 | 0.82 | TP53 (0.60) | — | |
| SCHEMBL13683745 | 0.75 | MCHR1 (0.93) | MCHR1EBPSIGMAR1BCHEACHE | |
| SCHEMBL4473605 | 0.75 | MAPT (0.70) | MCHR1EBPSIGMAR1BCHEACHE | |
| SCHEMBL30969207 | 0.75 | PARP10 (0.60) | EBPSIGMAR1BCHEACHELMNA | |
| SCHEMBL3149568 | 0.74 | EBP (0.69) | MCHR1EBPSIGMAR1BCHEACHE | |
| SCHEMBL250102 | 0.74 | EBP (0.69) | MCHR1EBPSIGMAR1BCHEACHE | |
| SCHEMBL30969305 | 0.74 | EBP (0.56) | MCHR1EBPSIGMAR1BCHEACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0997465-B1 | Azaindole derivatives and their use as antithrombotic agents | LILLY CO ELI (US) | 2004-02-04 | — | — | EP | disclosed |