Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 2/20 | 0.59 |
| ▸ | BCHE | P06276 | 6/20 | 0.58 |
| ▸ | ACHE | P22303 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221522 | 0.92 | TSHR (0.55) | THRATHRBTP53TSHR | |
| SCHEMBL6539277 | 0.89 | TP53 (0.60) | THRATHRBTP53TSHR | |
| SCHEMBL15535898 | 0.87 | THRA (0.63) | THRATHRBBCHEACHELMNA | |
| SCHEMBL15536155 | 0.83 | THRA (0.61) | THRATHRBBCHEACHELMNA | |
| SCHEMBL8477806 | 0.83 | MCHR1 (0.57) | BCHEACHELMNACHRM2HTR1A | |
| SCHEMBL2472562 | 0.82 | MAPT (0.66) | THRATHRBBCHEACHELMNA | |
| SCHEMBL434056 | 0.81 | L3MBTL1 (0.67) | THRATHRBBCHEACHELMNA | |
| SCHEMBL2472164 | 0.81 | TP53 (0.71) | THRATHRBBCHEACHETP53 | |
| SCHEMBL1984870 | 0.81 | DRD2 (0.56) | THRATHRBBCHEACHECYP1A2 | |
| Hydrochloric Acid SCHEMBL3853408 | 0.80 | TP53 (0.69) | THRATHRBBCHEACHETP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9238636-B2 | Process for preparation of dronedarone by Grignard reaction | SANOFI (FR) | 2016-01-19 | — | — | US | disclosed |
| US-20150274688-A1 | PROCESS FOR PREPARATION OF DRONEDARONE BY GRIGNARD REACTION | SANOFI (FR) | 2015-10-01 | — | — | US | disclosed |
| WO-2013178337-A1 | PROCESS FOR PREPARATION OF DRONEDARONE BY GRIGNARD REACTION | SANOFI (FR) | 2013-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274688-A1 | PROCESS FOR PREPARATION OF DRONEDARONE BY GRIGNARD REACTION | CYP3A4, CYP2C9, CYP4B1 | THRA 4251/4885THRB 4438/4885BCHE 2659/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.