Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478629 | 0.92 | HCAR3 (0.32) | — | |
| SCHEMBL8477853 | 0.83 | HCAR3 (0.30) | — | |
| SCHEMBL8475719 | 0.79 | HCAR3 (0.32) | — | |
| SCHEMBL8473663 | 0.76 | — | — | |
| SCHEMBL8478464 | 0.74 | — | — | |
| SCHEMBL8475635 | 0.73 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8474017 | 0.73 | UTS2R (0.30) | — | |
| SCHEMBL8719264 | 0.69 | ALDH1A1 (0.33) | ALDH1A1 | |
| SCHEMBL8474802 | 0.69 | PDE7A (0.35) | — | |
| SCHEMBL8477302 | 0.66 | HCAR3 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889002-A | CENTRAL NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; ENDOCRINAL DISEASES | NOVO NORDISK A/S (DK) | 1999-03-30 | — | — | US | disclosed |
| CN-1208417-A | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |