Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.30 |
| ▸ | KDM6B | O15054 | 1/20 | 0.30 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477864 | 0.73 | — | — | |
| SCHEMBL8478453 | 0.73 | ALDH1A1 (0.34) | — | |
| SCHEMBL8477669 | 0.71 | CHEK1 (0.31) | — | |
| SCHEMBL8475635 | 0.68 | ALDH1A1 (0.31) | — | |
| SCHEMBL8716334 | 0.67 | LIMK1 (0.31) | — | |
| SCHEMBL8474802 | 0.66 | PDE7A (0.35) | UTS2R | |
| SCHEMBL8477373 | 0.64 | ABCC8 (0.41) | — | |
| SCHEMBL7564894 | 0.60 | — | — | |
| SCHEMBL8477302 | 0.60 | HCAR3 (0.31) | UTS2RKDM6BKDM4C | |
| SCHEMBL8716380 | 0.59 | TLR8 (0.34) | UTS2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5889002-A | CENTRAL NERVOUS SYSTEM DISORDERS; CARDIOVASCULAR DISORDERS; RESPIRATORY SYSTEM DISORDERS; GASTROINTESTINAL DISORDERS; ENDOCRINAL DISEASES | NOVO NORDISK A/S (DK) | 1999-03-30 | — | — | US | disclosed |
| CN-1208417-A | Fused 1,2,4-thiadiazine and fused 1,4-thiazine derivatives, their preparation and use | NOVO NORDISK AS (DK) | 1999-02-17 | — | — | CN | disclosed |