Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LIMK1 | P53667 | 4/20 | 0.31 |
| ▸ | LATS1 | O95835 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8716322 | 0.82 | LIMK1 (0.32) | LIMK1 | |
| SCHEMBL8715972 | 0.78 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL8719336 | 0.74 | — | — | |
| SCHEMBL8716334 | 0.72 | LIMK1 (0.31) | LIMK1 | |
| SCHEMBL8478453 | 0.69 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8716380 | 0.64 | TLR8 (0.34) | — | |
| SCHEMBL8478629 | 0.62 | HCAR3 (0.32) | — | |
| SCHEMBL8715828 | 0.60 | MAPT (0.30) | — | |
| SCHEMBL4723579 | 0.59 | ALDH1A1 (0.42) | ALDH1A1LIMK1HTT | |
| SCHEMBL8826298 | 0.58 | ALDH1A1 (0.46) | ALDH1A1LATS1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876379-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997026265-A1 | FUSED 1,2,4-THIADIAZINE AND FUSED 1,4-THIAZINE DERIVATIVES, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1997-07-24 | — | — | WO | disclosed |