Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.51 |
| ▸ | MGLL | Q99685 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9013878 | 0.84 | DPP4 (0.49) | FAAHMGLLALOX15DPP4NR1H2 | |
| SCHEMBL8476770 | 0.84 | FAAH (0.53) | FAAHMGLLALOX15MAPTALDH1A1 | |
| SCHEMBL8481806 | 0.82 | MEN1 (0.49) | MGLLMAPTNR1H2NR1H3GRM4 | |
| SCHEMBL8475522 | 0.80 | FAAH (0.49) | FAAHMGLLALOX15MAPTALDH1A1 | |
| SCHEMBL7164266 | 0.74 | FAAH (0.49) | FAAHMGLLALOX15MAPTALDH1A1 | |
| SCHEMBL8479295 | 0.73 | MEN1 (0.55) | MAPTALDH1A1L3MBTL1DPP4P2RX7 | |
| SCHEMBL8668758 | 0.73 | FAAH (0.54) | FAAHMGLLALOX15MAPTALDH1A1 | |
| SCHEMBL8584295 | 0.72 | FAAH (0.47) | FAAHMGLLALOX15MAPTALDH1A1 | |
| SCHEMBL8664720 | 0.70 | MEN1 (0.52) | ALDH1A1L3MBTL1P2RX7GAAMEN1 | |
| SCHEMBL8666082 | 0.70 | KMT2A (0.54) | MGLLMAPTALDH1A1L3MBTL1GRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861517-A | INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEINS LEVELS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |