Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 2/20 | 0.37 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.37 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | HTR7 | P34969 | 5/20 | 0.33 |
| ▸ | HCAR1 | Q9BXC0 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8476770 | 0.78 | FAAH (0.53) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL8478820 | 0.74 | FAAH (0.51) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL8475522 | 0.72 | FAAH (0.49) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL8668758 | 0.71 | FAAH (0.54) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL7160839 | 0.70 | HSD17B10 (0.47) | ALOX15ALDH1A1MAPT | |
| SCHEMBL8584295 | 0.70 | FAAH (0.47) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL7164530 | 0.69 | MGLL (0.48) | FAAHMGLLALOX15ALDH1A1MAPT | |
| SCHEMBL7159612 | 0.69 | MEN1 (0.47) | ALDH1A1HTR7 | |
| SCHEMBL7162436 | 0.67 | MAPT (0.37) | ALDH1A1MAPTL3MBTL1 | |
| SCHEMBL3482778 | 0.67 | MGLL (1.00) | FAAHMGLLALOX15ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562814-B2 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | WYETH | 2003-05-13 | — | — | US | claimed |
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-23 | — | — | US | claimed |
| WO-2002028845-A1 | 3-THIOXO-[1,2,4]-OXADIAZINAN-5-ONE AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | WYETH (US) | 2002-04-11 | — | — | WO | claimed |
| US-6562814-B2 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | WYETH | 2003-05-13 | — | — | US | disclosed |
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AMERICAN HOME PRODUCTS CORPORATION | 2002-05-23 | — | — | US | disclosed |
| WO-2002028845-A1 | 3-THIOXO-[1,2,4]-OXADIAZINAN-5-ONE AND THEIR USE AS ANTI-ANTHEROSCLEROTIC AGENTS | WYETH (US) | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020061883-A1 | 3-thioxo-[1,2,4]-oxadiazinan-5-one derivatives | AHR, PAOX, PPARA | FAAH 740/4885MGLL 1703/4885ALOX15 1021/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.