Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.49 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8478820 | 0.82 | FAAH (0.51) | MEN1KMT2AMGLLLMNAMAPT | |
| SCHEMBL8478361 | 0.81 | MEN1 (0.61) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL8475120 | 0.80 | MEN1 (0.52) | MEN1KMT2AMGLLLMNAMAPT | |
| SCHEMBL8475279 | 0.79 | KMT2A (0.60) | MEN1KMT2AMGLLLMNAMAPT | |
| SCHEMBL8479295 | 0.73 | MEN1 (0.55) | MEN1KMT2ALMNAMAPTGAA | |
| SCHEMBL9013878 | 0.72 | DPP4 (0.49) | MEN1KMT2AMGLLLMNATSHR | |
| SCHEMBL8664720 | 0.70 | MEN1 (0.52) | MEN1KMT2ATSHRGAA | |
| SCHEMBL27558415 | 0.70 | MGLL (0.53) | MEN1KMT2AMGLLLMNAMAPT | |
| SCHEMBL8666082 | 0.70 | KMT2A (0.54) | MEN1KMT2AMGLLMAPTGAA | |
| SCHEMBL8475522 | 0.69 | FAAH (0.49) | MEN1KMT2AMGLLLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5861517-A | INCREASING BLOOD SERUM HIGH DENSITY LIPOPROTEINS LEVELS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1999-01-19 | — | — | US | disclosed |
| US-5554607-A | INCREASING HDL CHOLESTEROL | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-09-10 | — | — | US | disclosed |