Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TACR2 | P21452 | 9/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NPY1R | P25929 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8477279 | 0.91 | LMNA (0.51) | LMNAMAPTPKMTACR2KDM4E | |
| SCHEMBL8472213 | 0.90 | KDM4E (0.53) | LMNATACR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8476848 | 0.90 | KDM4E (0.48) | LMNATACR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8475932 | 0.90 | ALDH1A1 (0.52) | LMNATACR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8479146 | 0.89 | HTT (0.45) | LMNAKDM4ENPC1RAB9ASMN1; SMN2 | |
| SCHEMBL8474453 | 0.89 | LMNA (0.49) | LMNAMAPTPKMTACR2KDM4E | |
| SCHEMBL8472345 | 0.88 | SMN1; SMN2 (0.45) | LMNAMAPTPKMKDM4ENPC1 | |
| SCHEMBL8472229 | 0.88 | KDM4E (0.55) | LMNATACR2KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL8477079 | 0.85 | HTT (0.48) | KDM4ENPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL8472597 | 0.85 | ALDH1A1 (0.50) | LMNAMAPTKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5891902-A | OSTEOPOROSIS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1999-04-06 | — | — | US | disclosed |
| EP-0782989-A1 | INDOLE DERIVATIVES | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-07-09 | — | — | EP | disclosed |