Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KLK7 | P49862 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.51 |
| ▸ | PRKCA | P17252 | 1/20 | 0.50 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.50 |
| ▸ | PAM | P19021 | 1/20 | 0.50 |
| ▸ | LIPE | Q05469 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687870 | 0.94 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1MAPK1KLK7MAPT | |
| SCHEMBL7326238 | 0.87 | ALDH1A1 (0.70) | L3MBTL1ALDH1A1MAPK1MAPTALOX5 | |
| SCHEMBL1491531 | 0.85 | L3MBTL1 (0.59) | L3MBTL1ALDH1A1MAPK1MAPTALOX5 | |
| SCHEMBL12697639 | 0.85 | ALDH1A1 (0.59) | L3MBTL1ALDH1A1MAPK1KLK7MAPT | |
| SCHEMBL810045 | 0.85 | RAB9A (0.63) | L3MBTL1ALDH1A1MAPTPOLBMEN1 | |
| SCHEMBL28207459 | 0.85 | ALDH1A1 (0.77) | L3MBTL1ALDH1A1MAPK1ALOX5PRKCA | |
| SCHEMBL2658123 | 0.85 | ALDH1A1 (0.77) | L3MBTL1ALDH1A1MAPK1ALOX5PRKCA | |
| SCHEMBL20867886 | 0.85 | ALDH1A1 (0.77) | L3MBTL1ALDH1A1MAPK1ALOX5PRKCA | |
| SCHEMBL8605265 | 0.84 | L3MBTL1 (0.57) | L3MBTL1ALDH1A1MAPK1MAPTALOX5 | |
| SCHEMBL1171464 | 0.84 | ALDH1A1 (0.74) | L3MBTL1ALDH1A1MAPK1KLK7MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| US-5700801-A | ANTIINFLAMMATORY AGENTS, BONE DISORDERS | KARL THOMAE, GMBH (DE) | 1997-12-23 | — | — | US | disclosed |