Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | POLB | P06746 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALPG | P10696 | 3/20 | 0.44 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | BLM | P54132 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13247985 | 0.85 | LMNA (0.43) | L3MBTL1GAAKMT2AMAPTPOLB | |
| SCHEMBL25502419 | 0.82 | GAA (0.58) | L3MBTL1GAAKMT2AMAPTPOLB | |
| SCHEMBL6091601 | 0.81 | KMT2A (0.46) | L3MBTL1KMT2AMAPTPOLBMEN1 | |
| SCHEMBL8412699 | 0.80 | KMT2A (0.48) | L3MBTL1GAAKMT2AMAPTPOLB | |
| SCHEMBL9255582 | 0.79 | L3MBTL1 (0.45) | L3MBTL1GAAKMT2AMAPTPOLB | |
| SCHEMBL1372846 | 0.78 | P2RX1 (0.49) | KMT2AMAPTALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL7478345 | 0.78 | KMT2A (0.44) | KMT2AMAPTPOLBMEN1ALPG | |
| SCHEMBL5573253 | 0.78 | KMT2A (0.47) | L3MBTL1KMT2AMAPTPOLBMEN1 | |
| SCHEMBL8629800 | 0.78 | KMT2A (0.44) | KMT2AMAPTPOLBMEN1ALPG | |
| SCHEMBL30996203 | 0.78 | CYP1A2 (0.55) | KMT2AMAPTCYP1A2CYP2D6HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-60054388-A | — | — | None | — | — | JP | disclosed |
| US-11813338-B2 | Diagnosing and treating cancer | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2023-11-14 | — | — | US | disclosed |
| US-20160220703-A1 | DIAGNOSING AND TREATING CANCER | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2016-08-04 | — | — | US | disclosed |
| US-20140378533-A1 | MODULATION OF RNA BY REPEAT TARGETING | ISIS PHARMACEUTICALS, INC. (US) | 2014-12-25 | — | — | US | disclosed |
| WO-2014165216-A1 | DIAGNOSING AND TREATING CANCER | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2014-10-09 | — | — | WO | disclosed |
| US-5936016-A | SPIRO(INDOLINE(2,3')-NAPHTHOXAZINES) HAVING SPECIFIED SUBSTITUENT IN THE 6' POSITION; OPHTHALMIC OPTICS AND LENSES | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1999-08-10 | — | — | US | disclosed |
| EP-0772798-B1 | SPIRO INDOLINE- 2,3']-BENZOXAZINE]-TYPE PHOTOCHROMIC COMPOUNDS CONTAINING A 6'-CYANO OR PHENYLSULPHONYL GROUP AND WITH A 7', 8'-CONDENSED BENZENE RING IN THE BENZOXAZINE RING AND USE OF SAME IN OPHTHALMIC OPTICS | TRANSITIONS OPTICAL INC (US) | 1999-06-02 | — | — | EP | disclosed |
| EP-0772798-A1 | SPIRO INDOLINE- 2,3']-BENZOXAZINE]-TYPE PHOTOCHROMIC COMPOUNDS CONTAINING A 6'-CYANO OR PHENYLSULPHONYL GROUP AND WITH A 7', 8'-CONDENSED BENZENE RING IN THE BENZOXAZINE RING AND USE OF SAME IN OPHTHALMIC OPTICS | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1997-05-14 | — | — | EP | disclosed |
| WO-1996004590-A1 | SPIRO[INDOLINE-[2,3']-BENZOXAZINE]-TYPE PHOTOCHROMIC COMPOUNDS CONTAINING A 6'-CYANO OR PHENYLSULPHONYL GROUP AND WITH A 7', 8'-CONDENSED BENZENE RING IN THE BENZOXAZINE RING AND USE OF SAME IN OPHTHALMIC OPTICS | ESSILOR INTERNATIONAL COMPAGNIE GENERALE D'OPTIQUE (FR) | 1996-02-15 | — | — | WO | disclosed |
| US-5473068-A | Photochromic spirooxazine monomers and polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZMANN INSTITUTE OF SCIENCE (IL) | 1995-12-05 | — | — | US | disclosed |
| US-5322945-A | Photochromic spirooxazine monomers and polysiloxanes | YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) | 1994-06-21 | — | — | US | disclosed |
| JP-S6054388-A | PHOTOCHROMIC COMPOUND | SONY CORP | 1985-03-28 | — | — | JP | disclosed |
| US-4201707-A | Methine dyestuffs containing a phenyl azo group | BAYER AKTIENGESELLSCHAFT (DE) | 1980-05-06 | — | — | US | disclosed |
| US-4143228-A | RED SHADES | BAYER AKTIENGESELLSCHAFT (DE) | 1979-03-06 | — | — | US | disclosed |
| US-4138570-A | METHINE DYE | BAYER AKTIENGESELLSCHAFT (DE) | 1979-02-06 | — | — | US | disclosed |
| JP-S0654388-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160220703-A1 | DIAGNOSING AND TREATING CANCER | CHKA, CHKB, CILK1 | L3MBTL1 2748/4885GAA 1163/4885KMT2A 805/4885 |
| US-11813338-B2 | Diagnosing and treating cancer | CHKA, CHKB, CILK1 | L3MBTL1 2748/4885GAA 1163/4885KMT2A 805/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.