Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR2C | P28335 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8264357 | 1.00 | KDM4E (0.54) | KDM4EMAPTHPGDGAAPDGFRB | |
| SCHEMBL12326161 | 0.89 | PDGFRB (0.58) | KDM4EMAPTPDGFRBPDGFRAALDH1A1 | |
| SCHEMBL8338270 | 0.85 | ACHE (0.52) | KDM4EMAPTHPGDGAAPDGFRB | |
| SCHEMBL1912033 | 0.83 | DYRK1A (0.52) | KDM4EMAPTHPGDPDGFRBPDGFRA | |
| SCHEMBL15342387 | 0.83 | DYRK1A (0.52) | KDM4EMAPTHPGDPDGFRBPDGFRA | |
| SCHEMBL4635995 | 0.83 | KDM4E (0.50) | KDM4EMAPTHPGDGAAALDH1A1 | |
| SCHEMBL4533772 | 0.83 | L3MBTL1 (0.62) | KDM4EMAPTHPGDALDH1A1L3MBTL1 | |
| SCHEMBL15342384 | 0.83 | PDGFRB (0.57) | KDM4EMAPTHPGDPDGFRBPDGFRA | |
| SCHEMBL8401018 | 0.83 | PDGFRB (0.53) | KDM4EMAPTGAAPDGFRBPDGFRA | |
| SCHEMBL8418986 | 0.82 | RAB9A (0.48) | KDM4EMAPTHPGDGAAPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116253623-B | Direct cross-coupling method of aryl fluorine sulfate and aryl bromine | 南京工业大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-114591128-B | Direct cross-coupling method of aryl sulfide salt and aryl bromide | 南京工业大学 | 2023-08-22 | — | — | CN | disclosed |
| CN-114805674-B | Polymeric phosphine ligands, transition metal complexes comprising same, preparation and use thereof | 中国科学院上海有机化学研究所 | 2023-08-11 | — | — | CN | disclosed |
| CN-116253623-A | Direct cross-coupling method of aryl fluorine sulfate and aryl bromine | 南京工业大学 | 2023-06-13 | — | — | CN | disclosed |
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | GERO PTE. LTD. (SG) | 2023-02-16 | — | — | US | disclosed |
| CN-114805674-A | Polymeric phosphine ligands, transition metal complexes comprising same, preparation and use thereof | 中国科学院上海有机化学研究所 | 2022-07-29 | — | — | CN | disclosed |
| CN-114591128-A | Direct cross-coupling method of aryl sulfur salt and aryl bromide | 南京工业大学 | 2022-06-07 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230047816-A1 | PFKFB3 INHIBITORS AND THEIR USES | PFKFB3, PFKFB4, PFKFB1 | KDM4E 916/4885MAPT 845/4885HPGD 980/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.