Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8485382 | 0.89 | ALDH1A1 (0.41) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL9694976 | 0.88 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL7689949 | 0.82 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL8599203 | 0.78 | ALDH1A1 (0.43) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL8604172 | 0.77 | ALDH1A1 (0.39) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL8603446 | 0.76 | ALDH1A1 (0.34) | ALDH1A1MAPTGAAGLAKDM4E | |
| SCHEMBL8602482 | 0.76 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTHSD17B10KDM4E | |
| SCHEMBL9530045 | 0.76 | LMNA (0.57) | ALDH1A1HPGDMAPTGAAKDM4E | |
| SCHEMBL8603927 | 0.75 | ALDH1A1 (0.38) | ALDH1A1HPGDMAPTHSD17B10TP53 | |
| SCHEMBL8612176 | 0.75 | ALDH1A1 (0.34) | ALDH1A1HPGDMAPTHSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5883049-A | Hydantoin derivatives and herbicides containing said derivatives as active ingredient | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1999-03-16 | — | — | US | disclosed |
| EP-0801068-A1 | HYDANTOIN DERIVATIVES, PROCESS FOR PRODUCING THE SAME AND HERBICIDES COMPRISING THE SAME AS ACTIVE INGREDIENTS | SAGAMI CHEMICAL RESEARCH CENTER (JP) | 1997-10-15 | — | — | EP | disclosed |
| EP-0408382-B1 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL IND LTD (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5127935-A | Halogen, phenyl and heterocycle substituents, agricultural use | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| US-5084084-A | Uracil and thiouracil derivatives | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-01-28 | — | — | US | disclosed |
| EP-0408382-A2 | Uracil derivatives and herbicides containing the same as active ingredient | NISSAN CHEMICAL INDUSTRIES, LIMITED (JP) | 1991-01-16 | — | — | EP | disclosed |