Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.38 |
| ▸ | GABRE | P78334 | 1/20 | 0.38 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8487242 | 0.99 | HRH3 (0.39) | HRH3TPSAB1TPSD1TPSG1GABRP | |
| Hydrochloric Acid SCHEMBL9058907 | 0.77 | TPSAB1 (0.43) | HRH3TPSAB1TPSD1TPSG1CHRM4 | |
| SCHEMBL4155085 | 0.75 | TSHR (0.61) | HRH3GABRPGABRDGABRA1TSHR | |
| SCHEMBL8484135 | 0.73 | LMNA (0.39) | HRH3GABRPGABRDGABRA1TSHR | |
| Hydrochloric Acid SCHEMBL9058143 | 0.72 | POLB (0.49) | HRH3TSHRHSD17B10POLBITGB3 | |
| Hydrochloric Acid SCHEMBL8550451 | 0.70 | L3MBTL1 (0.47) | CHRM4MEN1KMT2AHSD17B10ITGB3 | |
| SCHEMBL8484147 | 0.70 | POLB (0.38) | HRH3TPSAB1TPSD1TPSG1GABRP | |
| SCHEMBL517371 | 0.69 | HRH3 (0.45) | HRH3GABRPGABRDGABRA1TSHR | |
| SCHEMBL16083486 | 0.68 | HSD17B10 (0.53) | MEN1KMT2AHSD17B10POLBEPHX2 | |
| SCHEMBL8486862 | 0.68 | ITGB3 (0.41) | HRH3TPSAB1TPSD1TPSG1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |
| CN-1183770-A | Piperazine derivatives, medicaments containing these compounds, their use and processes for their preparation | THOMAE GMBH DR K (DE) | 1998-06-03 | — | — | CN | disclosed |