Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.50 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.45 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.43 |
| ▸ | CES1 | P23141 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | GRK2 | P25098 | 1/20 | 0.41 |
| ▸ | JUN | P05412 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6707524 | 0.93 | LTA4H (0.58) | LTA4HTNFRSF1ACYP1A1CYP1B1KMT2A | |
| SCHEMBL7842474 | 0.86 | TNFRSF1A (0.64) | TNFRSF1ACYP1A1CYP1B1MAPTCES2 | |
| SCHEMBL11400165 | 0.82 | TNFRSF1A (0.77) | LTA4HTNFRSF1ACYP1A1CYP1B1MAPT | |
| SCHEMBL2794365 | 0.81 | TNFRSF1A (0.53) | TNFRSF1ACYP1A1CYP1B1KMT2AMAPT | |
| SCHEMBL7448677 | 0.77 | TNFRSF1A (0.53) | TNFRSF1ACYP1B1KMT2AMAPTMEN1 | |
| SCHEMBL4618020 | 0.74 | LTA4H (1.00) | LTA4HKMT2AMAPTMEN1TAAR1 | |
| SCHEMBL3053668 | 0.74 | LTA4H (0.76) | LTA4HKMT2AMEN1TAAR1CES2 | |
| SCHEMBL6934618 | 0.74 | ALDH1A1 (0.67) | LTA4HKMT2AMEN1TAAR1CYP1A2 | |
| SCHEMBL6934616 | 0.74 | ALDH1A1 (0.67) | LTA4HKMT2AMEN1TAAR1CYP1A2 | |
| SCHEMBL14064486 | 0.73 | LTA4H (0.51) | LTA4HKMT2AMAPTMEN1TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5916891-A | CYTOKINE MEDIATED DISEASES | SMITHKLINE BEECHAM CORPORATION (US) | 1999-06-29 | — | — | US | disclosed |