Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | PPARD | Q03181 | 1/20 | 0.45 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8483089 | 0.91 | HDAC3 (0.55) | KEAP1FFAR1MAPK1HDAC3ADRA1A | |
| SCHEMBL8488065 | 0.80 | AKR1B1 (0.46) | FFAR1CA12CA9MTNR1AMTNR1B | |
| SCHEMBL9014772 | 0.79 | PARK7 (0.41) | HSD17B10MAPTKDM4EALDH1A1POLB | |
| SCHEMBL9376982 | 0.75 | TDP1 (0.41) | MAPK1SMN1; SMN2HSD17B10MAPTKDM4E | |
| SCHEMBL9377612 | 0.73 | KMT2A (0.50) | MAPK1APEX1HSD17B10CA12CA9 | |
| SCHEMBL6535771 | 0.73 | CDC25A (0.56) | KEAP1FFAR1MAPK1SMN1; SMN2HDAC6 | |
| SCHEMBL9377745 | 0.71 | TDP1 (0.41) | ALDH1A1 | |
| SCHEMBL10607496 | 0.71 | PTPN1 (0.41) | MAPTKDM4EALDH1A1POLBHPGD | |
| SCHEMBL71453 | 0.71 | PTGER4 (0.68) | KEAP1FFAR1MAPK1HDAC3ADRA1A | |
| SCHEMBL9320715 | 0.70 | GPR84 (0.37) | HSD17B10CA12CA9ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5965575-A | N-aryl piperidine compounds as 5HT1B antagonists | ADIR ET COMPAGNIE (FR) | 1999-10-12 | — | — | US | disclosed |
| US-5134147-A | Antipsychotic agents | ADIR ET COMPAGNIE (FR) | 1992-07-28 | — | — | US | disclosed |
| US-5100902-A | Dopamine and Serotonin Antagonists, Antipsychotic Agents | ADIR ET COMPAGNIE (FR) | 1992-03-31 | — | — | US | disclosed |