Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | MMP12 | P39900 | 1/20 | 0.45 |
| ▸ | MMP13 | P45452 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 4/20 | 0.43 |
| ▸ | AGER | Q15109 | 1/20 | 0.42 |
| ▸ | AR | P10275 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124225 | 0.92 | ALDH1A1 (0.43) | ALDH1A1HPGDCYP11B2KDM4EMAPT | |
| SCHEMBL8117768 | 0.90 | MMP12 (0.52) | ALDH1A1HPGDCYP11B2KDM4EHIF1A | |
| SCHEMBL7821907 | 0.90 | CYP11B2 (0.42) | ALDH1A1HPGDCYP11B2KDM4EMAPT | |
| SCHEMBL8483057 | 0.90 | MMP12 (0.52) | ALDH1A1HPGDCYP11B2KDM4EHIF1A | |
| SCHEMBL7821910 | 0.90 | CYP11B2 (0.42) | ALDH1A1HPGDCYP11B2KDM4EMAPT | |
| SCHEMBL8117910 | 0.90 | MMP12 (0.52) | ALDH1A1HPGDCYP11B2KDM4EHIF1A | |
| SCHEMBL8481421 | 0.88 | MEN1 (0.52) | ALDH1A1CYP11B2MAPTMMP12MMP13 | |
| SCHEMBL8477371 | 0.88 | CYP19A1 (0.50) | ALDH1A1CYP11B2MAPTMMP12CYP19A1 | |
| SCHEMBL8109540 | 0.88 | MEN1 (0.52) | ALDH1A1CYP11B2MAPTMMP12MMP13 | |
| SCHEMBL8479732 | 0.88 | MEN1 (0.52) | ALDH1A1CYP11B2MAPTMMP12MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5977105-A | Compounds | ASTRA PHARMAEUTICALS LTD. (GB) | 1999-11-02 | — | — | US | disclosed |
| EP-0865431-A2 | COMPOUNDS | Astra Pharmaceuticals Limited (GB) | 1998-09-23 | — | — | EP | disclosed |
| WO-1997020815-A1 | COMPOUNDS | ASTRA PHARMACEUTICALS LTD. (GB) | 1997-06-12 | — | — | WO | disclosed |