Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LDHA | P00338 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 7/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9608231 | 0.81 | LDHA (0.40) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8485494 | 0.80 | RPS6KB1 (0.47) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9609099 | 0.80 | RPS6KB1 (0.52) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8491743 | 0.79 | RPS6KB1 (0.46) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8504575 | 0.79 | RPS6KB1 (0.46) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8490055 | 0.77 | KMT2A (0.61) | HTTMAPK1LMNASMN1; SMN2KMT2A | |
| SCHEMBL8490466 | 0.77 | RPS6KB1 (0.49) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8483358 | 0.76 | HTT (0.60) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL9609208 | 0.76 | RAB9A (0.40) | LDHAHTTMAPK1LMNASMN1; SMN2 | |
| SCHEMBL8484024 | 0.75 | EGFR (0.61) | HTTMAPK1LMNASMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2455371-A1 | 4-(3-BUTYNYL)AMINOPYRIMIDINE DERIVATIVES AS PEST CONTROL AGENTS FOR AGRICULTURAL AND HORTICULTURAL USE | SDS Biotech K. K. (JP) | 2012-05-23 | — | — | EP | disclosed |