Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7010720 | 0.91 | SMN1; SMN2 (0.53) | LMNASMN1; SMN2LTA4HEGFRL3MBTL1 | |
| SCHEMBL11454925 | 0.89 | LMNA (0.54) | LMNAKCNH2SMN1; SMN2HRH3LTA4H | |
| SCHEMBL17285917 | 0.84 | KMT2A (0.49) | HTR4KCNH2HRH3CYP1A2RAB9A | |
| SCHEMBL27887743 | 0.84 | HTR4 (0.48) | HTR4LMNAKCNH2HRH3CYP1A2 | |
| SCHEMBL11861074 | 0.84 | CYP1A2 (0.53) | HTR4LMNASMN1; SMN2CYP1A2RAB9A | |
| SCHEMBL27871503 | 0.83 | HTR4 (0.45) | HTR4LMNAKCNH2HRH3CYP1A2 | |
| SCHEMBL17284641 | 0.83 | SMYD3 (0.54) | HTR4LMNAKCNH2SMN1; SMN2HRH3 | |
| SCHEMBL22878317 | 0.83 | HTR4 (0.47) | HTR4LMNAKCNH2SMN1; SMN2HRH3 | |
| SCHEMBL9058323 | 0.82 | HTR4 (0.45) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL7372305 | 0.81 | ALDH1A1 (0.48) | SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922717-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1999-07-13 | — | — | US | disclosed |