Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 7/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484271 | 0.82 | HTR4 (0.44) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL17285917 | 0.82 | KMT2A (0.49) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL27887743 | 0.82 | HTR4 (0.48) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL11861074 | 0.81 | CYP1A2 (0.53) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL17284641 | 0.81 | SMYD3 (0.54) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL27871503 | 0.81 | HTR4 (0.45) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL22878317 | 0.81 | HTR4 (0.47) | HTR4CYP1A2RAB9AL3MBTL1 | |
| SCHEMBL11454925 | 0.81 | LMNA (0.54) | L3MBTL1 | |
| SCHEMBL9058678 | 0.80 | HTR4 (0.48) | HTR4 | |
| SCHEMBL20309224 | 0.78 | ALDH1A1 (0.46) | HTR4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996020173-A1 | PIPERAZINE DERIVATIVES, MEDICAMENTS CONTAINING THE SAME, THEIR USE AND PROCESS FOR PREPARING THE SAME | DR. KARL THOMAE GMBH (DE) | 1996-07-04 | — | — | WO | disclosed |