Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.35 |
| ▸ | TTPA | P49638 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487391 | 0.93 | ALOX5 (0.41) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8484773 | 0.90 | MAPT (0.33) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8487346 | 0.83 | PSEN1 (0.36) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8487252 | 0.83 | MAPT (0.32) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8488203 | 0.80 | KDM4E (0.34) | PPARGMAPT | |
| SCHEMBL8486948 | 0.73 | MAPT (0.44) | PPARGMAPTLMNACYP2C9CYP2C19 | |
| SCHEMBL8487799 | 0.72 | KDM4E (0.33) | MAPT | |
| SCHEMBL10281136 | 0.72 | MAPT (0.59) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL11925102 | 0.71 | MAPT (0.57) | PPARGMAPTMEN1KMT2ATDP1 | |
| SCHEMBL8485596 | 0.71 | ALOX5 (0.39) | PPARGMAPTMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | claimed |
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |