Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSEN1 | P49768 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PDE4A | P27815 | 1/20 | 0.32 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8484773 | 0.93 | MAPT (0.33) | PSEN1MEN1KMT2AMAPTALOX5 | |
| SCHEMBL8487391 | 0.90 | ALOX5 (0.41) | MEN1KMT2AMAPTALOX5TDP1 | |
| SCHEMBL8487252 | 0.87 | MAPT (0.32) | PSEN1MEN1KMT2AMAPTTDP1 | |
| SCHEMBL8484530 | 0.83 | PPARG (0.40) | MEN1KMT2AMAPTALOX5TDP1 | |
| SCHEMBL8487799 | 0.80 | KDM4E (0.33) | MAPTKDM4E | |
| SCHEMBL8484695 | 0.76 | PSEN1 (0.35) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL10752967 | 0.71 | ALOX5 (0.46) | PSEN1MEN1KMT2APDE4APDE3A | |
| SCHEMBL8486948 | 0.71 | MAPT (0.44) | MAPTPPARGKDM4E | |
| SCHEMBL8488203 | 0.70 | KDM4E (0.34) | MAPTPPARGKDM4E | |
| SCHEMBL11446495 | 0.70 | PSEN1 (0.47) | PSEN1MEN1KMT2APDE4APDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | claimed |