Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8487799 | 0.89 | KDM4E (0.33) | KDM4EMAPT | |
| SCHEMBL8487391 | 0.79 | ALOX5 (0.41) | MAPTPPARG | |
| SCHEMBL8486948 | 0.75 | MAPT (0.44) | KDM4EMAPTPPARG | |
| SCHEMBL8484773 | 0.71 | MAPT (0.33) | KDM4EMAPTPPARG | |
| SCHEMBL8487346 | 0.70 | PSEN1 (0.36) | KDM4EMAPTPPARG | |
| SCHEMBL6032172 | 0.65 | MAPT (0.53) | KDM4EMAPTPPARG | |
| SCHEMBL8857258 | 0.63 | KDM4E (0.40) | KDM4EMAPTPPARG | |
| SCHEMBL8484201 | 0.62 | SIGMAR1 (0.45) | KDM4EMAPT | |
| SCHEMBL7469293 | 0.62 | MAPT (0.56) | KDM4EMAPTPPARG | |
| SCHEMBL8523887 | 0.62 | MAPT (0.43) | KDM4EMAPTPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5925656-A | CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1999-07-20 | — | — | US | disclosed |