SCHEMBL8487252

SCHEMBL8487252

CCNC(CON1C(=O)SC(Cc2ccccc2)C1=O)CC1(C)CCc2c(C)c(OCc3ccccc3)c(C)c(C)c2O1

nearest known ligand 0.32

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
PSEN1 P49768 5/20 0.32
KDM4E B2RXH2 1/20 0.31
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8484773 0.93 MAPT (0.33) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL8487346 0.87 PSEN1 (0.36) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL8484530 0.83 PPARG (0.40) MAPTMEN1KMT2ATDP1PPARG
SCHEMBL8487391 0.77 ALOX5 (0.41) MAPTMEN1KMT2ATDP1PPARG
SCHEMBL8485088 0.76 ALOX5 (0.31) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL8487799 0.75 KDM4E (0.33) MAPTKDM4E
SCHEMBL6980261 0.68 PSEN1 (0.43) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL29670864 0.68 PSEN1 (0.44) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL11440558 0.68 PSEN1 (0.44) MAPTMEN1KMT2ATDP1PSEN1
SCHEMBL7843126 0.68 PSEN1 (0.44) MAPTMEN1KMT2ATDP1PSEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5925656-A CONTAINING A 2,4-DIOXOTRIAZOLIDINE RING DR. REDDY'S RESEARCH FOUNDATION (IN) 1999-07-20 US disclosed