Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 7/20 | 0.44 |
| ▸ | RAB9A | P51151 | 7/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | MPO | P05164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.44 |
| ▸ | NOX3 | Q9HBY0 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 2/20 | 0.43 |
| ▸ | CTH | P32929 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8486315 | 0.87 | MAPT (0.45) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8484747 | 0.85 | NPC1 (0.51) | MAPTGAAMEN1KMT2AKDM4E | |
| SCHEMBL8482019 | 0.85 | GAA (0.51) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8480626 | 0.85 | XDH (0.48) | MAPTGAAMEN1KMT2AKDM4E | |
| SCHEMBL8484222 | 0.85 | RAB9A (0.49) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8484216 | 0.85 | RAB9A (0.49) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8484282 | 0.84 | XDH (0.51) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8484617 | 0.81 | XDH (0.52) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8487763 | 0.77 | NOX3 (0.51) | MAPTALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8480366 | 0.77 | XDH (0.54) | MAPTALDH1A1GAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5990118-A | NOVEL PURINE COMPOUNDS AND TRIAZOLOPURINE COMPOUNDS WHICH INHIBIT XANTHINE OXIDASE; REMEDIES FOR HYPERURICEMIA, AND AS PREVENTIVE AND THERAPEUTIC AGENTS FOR GOUT | YAMASA CORPORATION (JP) | 1999-11-23 | — | — | US | disclosed |
| EP-0811624-A1 | PURINE COMPOUNDS AND XANTHINE OXIDASE INHIBITORS | YAMASA CORPORATION (JP) | 1997-12-10 | — | — | EP | disclosed |