Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 9/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | PPARD | Q03181 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6575223 | 0.80 | CTSS (0.46) | CTSSCTSKNQO2KDM4ASYK | |
| SCHEMBL22002108 | 0.79 | SYK (0.40) | PPARGPPARACTSSCTSKSYK | |
| SCHEMBL20860285 | 0.77 | FFAR2 (0.44) | PPARGPPARACTSSCTSKSYK | |
| SCHEMBL8485076 | 0.77 | CTSS (0.57) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL22703144 | 0.74 | PPARG (0.44) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL22703156 | 0.74 | PPARG (0.44) | PPARGPPARACYP2C9CYP2C19PPARD | |
| SCHEMBL27414019 | 0.74 | CTSS (0.48) | PPARGPPARACTSSCTSKMALT1 | |
| SCHEMBL6827827 | 0.73 | PTPRB (0.45) | — | |
| SCHEMBL6831591 | 0.73 | NPC1 (0.45) | PPARGPPARAMMP2 | |
| SCHEMBL6831647 | 0.73 | PTPRB (0.45) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5986132-A | Synthesis of carboxylic acid derivatives | BRITISH BIOTECH PHARMACEUTICALS LTD. (GB) | 1999-11-16 | — | — | US | disclosed |