Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.46 |
| ▸ | CTSK | P43235 | 2/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 9/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 9/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.44 |
| ▸ | KDM4A | O75164 | 1/20 | 0.44 |
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28395771 | 0.88 | CTSB (0.47) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL4367316 | 0.88 | CTSB (0.47) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL6165666 | 0.87 | CTSS (0.44) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL6445274 | 0.86 | CTSS (0.60) | CTSSCTSKCTSB | |
| SCHEMBL6444049 | 0.84 | CTSS (0.50) | CTSSCTSKCTSBKDM4AACACB | |
| SCHEMBL9525653 | 0.83 | CYP2D6 (0.58) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL28136984 | 0.81 | KDM4A (0.46) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL9526163 | 0.81 | ATM (0.56) | CTSSCTSKCTSBSLC6A2SLC6A4 | |
| SCHEMBL20016573 | 0.81 | ROCK2 (0.48) | CTSSCTSKCTSBACACBMEN1 | |
| SCHEMBL8485083 | 0.80 | PPARG (0.43) | CTSSCTSKKDM4ASYKNQO2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1409540-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2004-04-21 | — | — | EP | disclosed |
| WO-2002026774-A2 | MELANOCORTIN RECEPTOR LIGANDS | THE PROCTER & GAMBLE COMPANY (US) | 2002-04-04 | — | — | WO | disclosed |